Can i take coq10 with plavix

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Answer: CoQ10 may interfere with warfarin treatment, although the evidence is mixed. There are some reports suggesting that CoQ10 decreases the effectiveness of warfarin Coumadin , which could necessitate an increase in warfarin dosage. On the other hand, there's a study which suggests the opposite that CoQ10 may increase the risk of bleeding when on warfarin. And another study suggests no effect so long as your INR bleeding time is stable.

To play it safe, consult with your doctor about using CoQ10 with warfarin. However, it's not clear whether it CoQ10 affects Plavix treatment. Join today to unlock all member benefits including full access to all CL Answers and over 1, reviews. Join now at www.

If you are currently being treated with any of the following medications, you should not use CoQ10 without first talking to your health care provider. Daunorubicin and doxorubicin -- Coenzyme Q10 may help to reduce the toxic effects on the heart caused by daunorubicin Cerubidin and doxorubicin Adriamycin , two chemotherapy medications that are commonly used to treat several kinds of cancer. Always speak to your oncologist before taking antioxidants along with chemotherapy.

Blood pressure medications -- In a clinical study of individuals taking blood pressure medications, including diltiazem Cardizem , metoprolol Lopressor or Toprol , enalapril Vasotec , and nitroglycerin Nitrostat or Nitrobid , CoQ10 supplementation allowed the individuals to take lower dosages of these drugs. This suggests that CoQ10 may enhance the effectiveness of certain blood pressure medications, but more research is needed to verify these results. Blood-thinning medications -- There have been reports that coenzyme Q10 may decrease the effectiveness of blood-thinning medications such as warfarin Coumadin or clopidigrel Plavix , leading to the need for increased doses.

In a clinical study of people taking blood pressure medications, adding CoQ10 supplements allowed them to reduce the doses of these medications. More research is needed, however. If you take medication for high blood pressure, talk to your provider before taking CoQ10, and DO NOT stop taking your regular medication.

Blood-thinning medications: There have been reports that CoQ10 may make medications such as warfarin Coumadin or clopidigrel Plavix less effective at thinning the blood.

If you take blood thinners, ask your provider before taking CoQ Betaxolol Betoptic : CoQ10 supplements may reduce the heart-related side effects of betaxolol drops Betoptic , a beta-blocker medication used to treat glaucoma, without making the medication any less effective. Metabolism, ubiquinone synthesis, and longevity. Genes Dev. Beal MF. Therapeutic effects of coenzyme Q10 in neurodegenerative diseases.

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Am J Health-System Pharm. Coenzyme Q 10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr.

Otolaryngol Head Neck Surg. The effect of conenzyme Q10 in patients with congestive heart failure. Ann Int Med. The effect of coenzyme Q10 supplementation on metabolic status of type 2 diabetic patients.

Minerva Gastroenterol Dietol. Conezyme Q10 and male infertility: a meta-analysis. J Assist Reprod Genet. Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation.

Nutr J. Coenzyme Q10 for heart failure. Cochrane Database Syst Rev. McCarty MF. Toward practical prevention of type 2 diabetes. Med Hypotheses. Nahas R. Herbal supplements can have strong effects in the body. Some can interact with prescription medications used to treat heart and circulatory problems, such as high blood pressure and heart failure. Some of these interactions can even be dangerous. About half of U. But research suggests that most don't tell their doctors about this use — even those who also take prescription medications.

Yet many herbal supplements may interact with prescription medications, including some used to prevent or treat heart disease. That's why it's so important to talk with your doctor before taking herbal supplements if you take prescription medications.

Your doctor and your pharmacist can help you avoid risky interactions. Several popular herbal supplements interact with common heart medications. This list covers only some interactions. It's important to talk to your doctor before taking any herbal supplements if you take prescription medications. If your doctor tells you it's OK to use an herbal supplement combined with a medication, make sure you follow dosing instructions carefully.

Watch for any signs that you could be having a drug interaction, such as:. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. A single copy of these materials may be reprinted for noncommercial personal use only.